The following are events related to the Global War On Terrorism (GWOT) that took place on this day.

2004

• Operation Devil Clinch in Iraq

2009

• Start of Operation New Hope in Iraq

Casualties on February 21:

• DAY, DAVID FREDRICK – February 21, 2005
• LHOTKA, JESSE MARVIN – February 21, 2005
• OLSON, JOHN THOMAS – February 21, 2005
• TIMMERMAN, JASON GARY – February 21, 2005
• FITZGERALD, ALMAR LARON – February 21, 2006
• JOHNS, JASON DOUGLAS – February 21, 2007
• WEAVER, DREW WILLIAM – February 21, 2008
• BAUM, MARK CONRAD – February 21, 2009
• GORRA, MARCOS ANTONIO – February 21, 2010
• HANSON, MATTHIAS NUMON – February 21, 2010
• PEAK, ADAM DANIEL – February 21, 2010
• SALVACION, JR – February 21, 2010
• WARD, ERIC LEVI – February 21, 2010
• ALFORD, MARCUS RAY SR – February 21, 2010
• GRINDER, BILLIE JEAN – February 21, 2010
• SISSON, ROBERT CURTIS JR – February 21, 2011
• MCKENNA, ALLEN ROBERT JR – February 21, 2012