The following are events related to the Global War On Terrorism (GWOT) that took place on this day.

Casualties on September 27:

• COX, GREGORY ALAN – September 27, 2004
• SICKELS, KENNETH LEE – September 27, 2004
• VILLANUEVA, JOSELITO ONAS – September 27, 2004
• BENFORD, JASON A – September 27, 2005
• LYONS, JAMES NATHANIEL – September 27, 2006
• JOHNSON, RANDY LEWIS JR – September 27, 2007
• BRYANT, JA’MEL ANTWON – September 27, 2008
• MANES, PHILIP FRAZIER – September 27, 2015